October 9, 2024
PET

SODIUM LACTATE

SODIUM LACTATE

SODIUM LACTATE

CAS number: 72-17-3 / 867-56-1
EC number: 200-772-0 / 212-762-3
Chemical formula: NaC3H5O3
Molar mass: 112.06 g/mol

Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste.
Sodium lactate is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting lactic acid to create a compound having the formula NaC3H5O3.
Sodium lactate is the sodium salt of L(+)-lactic acid, obtained by neutralisation of the acid of natural origin with a high purity sodium source.
Sodium lactate is produced naturally by living organisms as a by-product of the glycolysis.
Sodium lactate is a safe preservative with a high water holding capacity and buffering properties for food and personal care uses.
Sodium lactate, from Jungbunzlauer, is the sodium salt of L(+)-lactic acid, obtained by neutralisation of the acid of natural origin with a high purity sodium source.

Usage
As a food additive, sodium lactate has the E number E325 and is naturally a liquid product, but also is available in powder form.
Sodium lactate acts as a preservative, acidity regulator, and bulking agent.
Sodium lactate is sometimes used in shampoo products and other similar items such as liquid soaps, as Sodium lactate is an effective humectant and moisturizer.
Sodium lactate is used to treat arrhythmias caused by overdosing of class I antiarrythmics, as well as pressor sympathomimetics which can cause hypertension.
Sodium lactate also can be given intravenously as a source of bicarbonate for preventing or controlling mild to moderate metabolic acidosis in patients with restricted oral intake (for sodium bicarbonate) whose oxidative processes are not seriously impaired.
However, the use in lactic acidosis is contraindicated.
Sodium lactate can cause panic attacks in patients with existing panic disorder.
Sodium lactate is on the World Health Organization’s List of Essential Medicines, the safest and most effective medicines needed in a health system.

Sodium lactate, also known as mediject L or E325, belongs to the class of organic compounds known as carboxylic acid salts.
These are ionic derivatives of carboxylic acid.
Sodium lactate is an extremely weak basic (essentially neutral) compound (based on its pKa).
Sodium lactate is an odorless tasting compound.

Sodium Lactate is a liquid salt that is naturally derived from the fermentation of natural sugars.
In Cold Process soap, Sodium Lactate helps to produce a harder bar of soap that lasts longer in the shower.
As a salt, Sodium lactate is also a natural humectant, providing moisture.
This makes Sodium lactate a great additive to lotions, typically replacing glycerin in the recipe.
Sodium lactate is supplied as a 60% aqueous solution.

Preferred IUPAC name: Sodium 2-hydroxypropanoate
Other names: Sodium DL-lactate; Lactic acid sodium salt; E325

Sodium lactate (5%) used in neutral culture media has an antimicrobial effect which rises above that what would be expected from Sodium lactates water activity lowering effect.
This antimicrobial effect was found to exist towards various lactic acid bacteria,Staphylococcus aureus, and Salmonella typhimurium.
Sodium lactate is particularly evident from increased lag phase, decreased growth yield, and somewhat less from decreased growth rate.
Adverse growing conditions, such as suboptimum temperature, increase Sodium lactates anti-microbial effect.Escherichia coli is an exception, as Sodium lactates growth rate is hardly affected by 5% sodium lactate, although Sodium lactates growth yield is lowered.
The antimicrobial activity of sodium lactate evidently reflects how various micro-organisms can cope with this compound.

Sodium Lactate uses include Acne Treatments, Anti Ageing Creams & Lotions, Antimicrobial, Baking, Bread, Buffer, Cake Mixes, Conditioners, Cosmetics, Cupcakes, Dialysis Solutions, Exfoliant Scrub, Eye Drops, Facial Cleaner, Hair Conditioner, Hand Creams, Humectant, Kidney Dialysis Solution, Masks Cosmetic, Meat Products, Moisturizing Cream Formulations, Poultry, Preservative, Shampoo, Shampoo Sulfate Free, Skin Care Products, Sunscreens -Water Resistant.
Sodium lactate solution can be a proper draw solution for food processing.

Food and Nutrition: Sodium lactate is used as a food additive
Personal Care: Sodium lactate is used as a preservative enhancer, buffering agent, and a humectant moisturizer.
Sodium lactate is used as a food additive.
Personal Care: Sodium lactate is used as a preservative enhancer, buffering agent, and a humectant moisturizer
Pharmaceutical: Sodium lactate is used for parenteral applications and other dialyses solutions.
Sodium lactate acts as an electrolyte or alkalizing agent
Other: Sodium lactate has antimicrobial properties, humectant, produced by fermentation of sugar.

What Is Sodium lactate?
Glycolic Acid and Lactic Acid are naturally occuring organic acids also known as Alpha Hydroxy Acids or AHAs.
The salts of Glycolic Acid (Ammonium Glycolate, Sodium Glycolate), the salts of Lactic Acid (Ammonium Lactate, Calcium Lactate, Potassiu Lactate, Sodium Lactate, TEA-Lactate) and the esters of Lactic Acid (Methyl Lactate, Ethyl Lactate, Butyl Lactate, Lauryl Lactate, Myristyl Lactate, Cetyl Lactate) may also be used in cosmetics and personal care products.
In cosmetics and personal care products, these ingredients are used in the formulation of moisturizers, cleansing products, and other skin care products, as well as in makeup, shampoos, hair dyes and colors and other hair care products.

Why is Sodium lactate used in cosmetics and personal care products?
The following functions have been reported for Glycolic Acid, Lactic Acid and their salts and esters.

Buffering agent -Ammonium Lactate, Potassium Lactate, Sodium Lactate
Cosmetic astringent -Calcium Lactate
Exfoliant -Glycolic Acid, Lactic Acid, Ammonium Glycolate, Ammonium Lactate, Calcium Lactate, Potassium Lactate, Sodium Lactate
Humectant -Lactic Acid
pH adjuster -Glycolic Acid, Lactic Acid, Ammonium Glycolate, Sodium Glycolate
Skin conditioning agent -emollient -Lauryl Lactate, Myristyl Lactate, Cetyl Lactate
Skin conditioning agent -humectant -Lactic Acid, Ammonium Lactate, Potassium Lactate, Sodium Lactate, TEA-Lactate
Skin conditioning agent -miscellaneous -Lactic Acid
Solvent -Methyl Lactate, Ethyl Lactate, Butyl Lactate

Scientific Facts:
Glycolic Acid and Lactic Acid are alpha hydroxy acids (AHAs).
They may be either naturally occurring or synthetic.
They are often found in products intended to improve the overall look and feel of the skin.
Glycolic acid is the most widely used of out of the group and is usually manufactured from sugar cane.
Lactic acid, derived primarily from milk and its origins can be traced back to Cleopatra, who purportedly used sour milk on her skin.

What is Sodium Lactate?
Sodium Lactate is a naturally occurring humectant derived from the salt of Lactic Acid.
Despite the similar name, Sodium Lactate and Lactic Acid have very different chemical formulas; however what they do have in common is their excellent humectant properties.
Fade Out has specifically combined these ingredients in our formulations to provide the ultimate moisturisation.
Sodium Lactate is a natural component that can be found within the upper layers of your skin and contributes to the skins Natural Moisturising Factor (NMF).
The NMF helps to keep your skin hydrated, supple and smooth by maintaining hydration levels.

What does Sodium Lactate do?
Sodium Lactate is a superior humectant moisturiser with over twice the water holding ability than Glycerin.
Sodium lactate replenishes moisture by attracting and retaining water within the skin, preventing Sodium lactate from becoming dehydrated, dry and flaky.
Some studies have shown that using Sodium Lactate can increase the moisture content within the skin by a minimum of 84%.

Sodium Lactate also acts as a buffering agent which works by balancing the formulations pH levels to maintain healthy skin.
The normal pH for your skin ranges from pH 4 to 6; when this is out of balance and too acidic or alkali, Sodium lactate can cause sensitivities and depletes the skin of Sodium lactates natural protectant barrier.
The skins natural barrier is essential to maintain its daily functions, whilst preventing water from being lost, and protecting Sodium lactate from harmful pollutants.

Sodium lactate is the sodium salt of lactic acid and is already a favorite among soap makers.
But did you know sodium lactate is a “natural moisturizing factor” component of skin?
Sodium lactates a natural humectant added to lotions and creams as a less sticky alternative to glycerin.
Sodium lactate has the ability to hold more water than glycerin, sorbitol, and sodium PCA.
The only thing better at attracting water is hyaluronic acid.
According to online reports, the sodium of lactic acid have a higher level of inhibiting pathogen growth than the actual lactic acid itself, in food.
Sodium lactate is used to push off spoiling for as long as possible because Sodium lactate has the ability to extend the shelf life of meat and poultry!
So imagine how good it would be to add this, along with your broad spectrum preservative, to help keep the creepy crawlers out of your DIY skin creams and lotions.

Benefits of Sodium Lactate for your skin
Whilst Hyaluronic Acid still holds Sodium lactates place as the number one ingredient for moisturisation, Sodium Lactate follows closely behind.
Sodium lactates ability to attract water and prevent Sodium lactate from evaporating prevents and protects the skin from becoming dehydrated to help your skin look and feel soft, smooth and radiant with a healthy looking glow.

Intensely hydrates dry and dehydrated skin
Retains water to refine and nourish the complexion.
Prevents moisture loss
Brighten the complexion with a healthy, hydrated glow
Maintains a healthy pH level

Is Sodium Lactate right for my skin?
Sodium Lactate is suitable for all ages and skin types.
Sodium lactate is particularly beneficial to those who have dry skin or dehydrated skin.
We would always recommend performing a 48 hour patch test before using new products in your skincare regime.

In Food Production
Sodium Lactate E325 can used as preservative and pH regulator in food production.

In Beverage
Sodium Lactate E325 can be used as preservative, flavor enhancer, PH regulator in beverage.

In Pharmaceutical
Sodium Lactate E325 can be used as PH regulator in Pharmaceutical.

In Health and Personal care
Sodium Lactate E325used in the formulation of moisturizers, cleansing products, and other skin care products, as well as in makeup, shampoos, hair dyes and colors and other hair care products in cosmetic and personal care products.

In Agriculture/Animal Feed/Poultry
Sodium Lactate E325 can be used in Agriculture/Animal Feed/Poultry feed.

In Other Industries
Sodium lactate E325 is used to treat arrhythmias caused by overdosing of class I antiarrythmics, as well as pressor sympathomimeticswhich can cause hypertension.

CAS Number: 72-17-3
CHEBI:75228
ChEMBL: ChEMBL1357
ChemSpider: 6049
ECHA InfoCard: 100.000.702
E number: E325 (antioxidants, …)
PubChem CID: 6286
UNII: TU7HW0W0QT
CompTox Dashboard (EPA): DTXSID6052829

Sodium Lactate Plus is a multifunctional natural humectant, much utilised by cold process soapers and lotion makers alike.
Sodium lactate allows slightly soft soap recipes to release from the mould more easily (when using intricate moulds or the cube design), increases lather and adds mildness.
Sodium lactate is also a good substitute for glycerine in skin care formulations adding moisture and light conditioning.
Sodium Lactate is a sodium salt of natural L(+)-lactic acid, which is produced by fermentation of sugar.
Sodium lactate has a mild saline taste and has a neutral pH.
We have chosen this specialised Sodium Lactate ingredient because of the inclusion of Sodium Gluconate, which contributes skin conditioning.

Sodium Lactate Plus is an excellent inclusion in all bar soaps, bath, skin care and hair care products.
Because Sodium Lactate Plus has water binding capability and contributes an emollient feel, this makes Sodium lactate a sought after natural ingredient in salon and spa quality products.
Tests have shown Sodium lactate is an effective ingredient in hair detanglers.
Even in rinse off products, Sodium Lactate Plus dramatically improves the moisture content of the skin.
For soapers, Sodium Lactate Plus is an excellent mould release assistant!
Sodium lactate’s inclusion is a must for hard to unmould and silicone moulds as there is little evaporation from silicone log and loaf moulds.
I use 1 -2% in most of my recipes.
Sodium lactate’s natural and doesn’t affect trace at all!

Sodium Lactate Plus offers these benefits in your lotions, bath & body products:
-Skin friendliness -produces a milder bar soaps with reduced TEWL (trans epidermal water loss)
-Skin Conditioning -in bar soaps, lotions, hair care products
-Boosts lather, and produces a more luxurious, creamy stable foam in soaps
-Extends usage life of bar soaps
-Hardens oil-based bar soaps
-Humectant qualities -in all soaps, skincare and hair care products
-Suitable for Vegans

Regarding milk
Despite the similarity in name, sodium lactate is not chemically similar to lactose (milk sugar), so need not be restricted by those with lactose intolerance.
In general, lactates such as sodium, calcium, and potassium lactate are salts derived from the neutralization of lactic acid and most commercially used lactic acids are fermented from dairy-free products such as cornstarch, potatoes, or molasses.
Sugar or tapioca additionally may be used.
In some rare instances, some lactic acid is fermented from dairy products such as whey and lactose.
Whey is made of up 6.5% solids of which 4.8% is solid lactose.
Waste whey is infrequently used to produce lactic acid when the whey itself is produced as waste during the manufacture of certain dairy products.
Such dairy-type lactic acid generally goes back into dairy products, such as ice cream and cream cheese, rather than into nondairy products.
Moreover, although the lactic-acid starter culture to ferment corn or beets may contain milk, sodium lactate does not contain milk protein and need not be restricted by someone avoiding milk or those with a milk allergy.

What is sodium lactate?
Sodium lactate is a natural sodium salt of lactic acid.
Sodium lactates chemical formula is NaC3H5O3, and its CAS Number is 72-17-3.
Sodium lactates IUPAC name is sodium 2-hydroxypropanoate, and Sodium lactate may also be referred to as either sodium DL-lactate or lactic acid sodium salt.
Sodium lactate is found naturally in the stratum corneum of human skin.

Sodium L-lactate is produced from pyruvate by the enzyme Lacate Dehydrogenase.
Lactate production occurs during anaerobic glycolysis or in proliferatively active cells.

What is Sodium Lactate?
Sodium Lactate, a 60% concentration in water, and is the sodium salt of natural Lactic Acid, produced through the fermentation of sugar, an alpha hydroxy acid that occurs everywhere in nature.
Sodium lactate is naturally produced in the skin and also occurs naturally in all animal and human muscle tissue.

What are its benefits to the skin and how is Sodium lactate used Sodium lactate the cosmeceutical industry?
Sodium Lactate is one of the Natural Moisturizing Factor of the skin, required in the maintenance of natural hydration.
Sodium Lactate is a superior moisturizer, increasing the moisture content of skin by up to 84%.
Sodium Lactate is also known to reduce irritation and increases the efficacy of alpha and beta hydroxy acids.
Sodium lactate is widely used as Sodium lactate significantly increases and accelerates the skin lightening action of Vitamin C in skin products.
With its water binding capacity, Sodium lactate dramatically improves the moisture content of the skin and also Sodium lactates antimicrobial action and ability to inhibit bacteria development, and is seen in cosmetics and beauty products, especially shampoos and liquid cleansers, as a preservative, buffering agent, pH controlling agent, or exfoliant.

Chemical formula: C3H5NaO3
Molar mass: 112.06 g/mol
Appearance: White powder
Density: 1.33 g/mL, 1.31 g/ml (60 % syrup)
Melting point:
161 to 162 °C (322 to 324 °F; 434 to 435 K)
17 °C (60 % syrup)
Boiling point: 113 °C (235 °F; 386 K) (60 % syrup
Solubility in water: > 1.5 g/mL

Sodium lactate
Synonyms: Sodium L-lactate, L-Lactic acid sodium salt, (S)-2-Hydroxypropionic acid sodium salt, Sarcolactic acid sodium salt
CAS Number: 867-56-1
Molecular Weight: 112.06
Beilstein Registry Number: 4567087
Empirical Formula (Hill Notation): C3H5NaO3

What is Sodium lactate?
Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste.

What does Sodium lactate do?
Sodium lactate is often used as a preservative or pH buffer in foods but has moisturizing properties that make Sodium lactate useful in gentle cleansers and creams.
We use Sodium lactate in our bodywash to provide gentle cleansing and aid in preservation.

How is Sodium lactate made?
Our Stewardship Model guides us to select ingredients which have been processed in a manner that supports our philosophy of human and environmental health.
Sodium lactate is most often made by the fermentation of a sugar, which can come from corn or beets, to produce lactic acid.
Tom’ uses a sodium lactate derived from corn.
The fermentation product, lactic acid, is neutralized to create sodium lactate.
Although Sodium lactate can be prepared by fermentation of milk or whey protein, that is not often the case and the resultant fermentation product will not contain any residual milk protein.

What are the alternatives?
We use a number of different natural moisturizers in our products, one of the primary ingredients is vegetable-based glycerin.
There are also moisturizers on the market which would not meet our Stewardship guidelines, such as diethylene glycol.

Sodium lactate is also used in patients as a source of bicarbonate in the treatment of mild to moderate metabolic acidosis associated with dehydration or associated with potassium deficiency.
These solutions are indicated as methods of intravenous drug delivery, if the drugs are compatible with the solutions.

Is Sodium lactate is the right option for me?
Sodium lactate should not be confused with dairy or lactose.
Sodium lactate is not chemically similar and is safe for those individuals looking to avoid lactose.
This product is often available with an added preservative to ensure stability but Tom’s partnered with the supplier to develop an ingredient that was naturally preserved to meet our strict Stewardship requirements.

What Are The Benefits Of Sodium Lactate?
In cosmetics and skincare products, sodium lactate functions as a preservative enhancer, buffering agent, and a humectant moisturizer.

Preservative
Sodium lactate acts as a bacteriostatic agent, which means that Sodium lactate stops bacteria from reproducing, while not necessarily killing them otherwise.
Therefore, sodium lactate is not an effective preservative when used alone; Sodium lactate must be used in addition to a full spectrum preservative.
The ability to preserve a cosmetic formulation is important, not only to extend the product’s shelf life, but also to prevent microbial contamination.
Cosmetics have a high potential for microbial contamination, especially creams and lotions that are packaged in jars, opened frequently, and applied to the skin with the fingers.
Plus, the ingredients used in cosmetic formulations, such as water, oils, peptides, and carbohydrates, create the perfect environment for microorganism growth.

pH
Sodium lactate also functions as a buffering agent, which means Sodium lactate will help establish and hold the pH of a product.
As you may remember from high school science classes, pH stands for ‘potential hydrogen’ and it refers to the level of acidity or alkalinity in a given solution.
The pH scale ranges from 0 to 14.
A pH of 7 is neutral, while a pH less than 7 is acidic and a pH greater than 7 is basic or alkaline.
Sodium lactate is important to balance the pH of cosmetics and skin care products in order to maintain the skin’s normal pH, typically between 4.75 and 5.5, as closely as possible.
If a product is too acidic, Sodium lactate may irritate the skin or cause a stinging sensation.
However, if a product is too alkaline Sodium lactate can deplete the skin of essential lipids or oils and may also make the skin more susceptible to acne.

Moisture
Another function of sodium lactate is as a humectant moisturizer.
A humectant is a water-absorbing ingredient that often has a molecular structure that allows Sodium lactate to easily bind with water molecules.
This structure allows humectants to attract and retain the moisture in the air nearby via absorption, drawing the water vapor into or beneath the surface.
As a humectant, sodium lactate helps keep the skin hydrated and has been reported to increase the moisture content of skin by up to 84%.
Sodium lactate is similar in function to hyaluronic acid and glycerin, both great humectant ingredients.

Is Sodium Lactate Vegan?
Sodium lactate is generally considered to be a vegan ingredient.
Sodium lactate is not derived from animal or animal by-product sources.
If you are looking for a vegan product make sure to research the other ingredient in the product and ensure that the brand is cruelty-free.

Is Sodium Lactate Safe?
The safety of alpha hydroxy acids, including sodium lactate, has been assessed by the Cosmetic Ingredient Review Expert Panel.
The Cosmetic Ingredient Review Expert Panel is a group responsible for the independent evaluation of skincare and cosmetic ingredient safety.
The Panel evaluated the scientific data and concluded that lactic acid and Sodium lactates salts (i.e. sodium lactate) were safe for use in cosmetics and skincare products, but with some restrictions.
The concentrations must be 10% or less and the final formulation must have a pH of 3.5 or greater.
Furthermore, the product should be formulated to avoid increasing sun sensitivity, or include directions for use that include the daily use of sun protection.

compound sodium lactate solution
SODIUM LACTATE
72-17-3
Sodium DL-lactate
Lactic acid sodium salt
Monosodium lactate
Lactic acid, monosodium salt
Lacolin
Per-glycerin
sodium 2-hydroxypropanoate
Sodium alpha-hydroxypropionate
Monosodium 2-hydroxypropanoate
Propanoic acid, 2-hydroxy-, monosodium salt
DL-Lactic acid sodium salt
Sodium (dl)-lactate
CCRIS 7316
312-85-6

Sodium Lactate 60 in Sodium L(+)-Lactate Personal Care Grade is the sodium salt of L(+)-lactic acid, obtained by neutralisation of the acid of natural origin with a high purity sodium source.
Lactate is produced naturally by living organisms as a by-product of the glycolysis.
Jungbunzlauer sodium L(+)-lactate is an effective moisturiser with a high water holding capacity and buffering properties for personal care uses.

Sodium Lactate Description
Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is a sterile, nonpyrogenic, concentrated solution of Sodium Lactate in water for injection.
The solution is administered after dilution by the intravenous route as an electrolyte replenisher and systemic alkalizer.
Sodium lactate should not be administered undiluted.
Each 10 mL vial contains Sodium Lactate, anhydrous 5.6 g (50 mEq each of Na+ and lactate anion).
The solution contains no bacteriostat, antimicrobial agent or added buffer.
Contains hydrochloric acid for pH adjustment.
The osmolar concentration is 10 mOsmol/mL (calc.).
When diluted with water for injection to make a 1/6 molar solution, the pH of Sodium Lactate injection is 6.5 (6.0 to 7.3).

Sodium Lactate, USP is chemically designated CH3CH(OH)COONa, a 60% aqueous solution miscible in water.
The sodium salt of lactic acid.
Sodium lactate’s a great skin moisturizer and also used to regulate the pH value of the cosmetic formula.
Sodium lactate’s a natural ingredient approved by both ECOCERT and COSMOS.

The semi-rigid vial is fabricated from a specially formulated polyolefin.
Sodium lactate is a copolymer of ethylene and propylene.
The safety of the plastic has been confirmed by tests in animals according to USP biological standards for plastic containers.
The container requires no vapor barrier to maintain the proper drug concentration.

Sodium Lactate -Clinical Pharmacology
Lactate anion [CH3CH(OH)COO−] serves the important purpose of providing “raw material” for subsequent regeneration of bicarbonate (HCO3−) and thus acts as a source (alternate) of bicarbonate when normal production and utilization of lactic acid is not impaired as a result of disordered lactate metabolism.
Lactate anion is usually present in extracellular fluid at a level of less than 1 mEq/liter, but may attain a level of 10 mEq/liter during exercise.
Sodium lactate is seldom measured as such and thus is one of the “unmeasured anions” (“anion gap”) in determinations of the ionic composition of plasma.
Since metabolic conversion of lactate to bicarbonate is dependent on the integrity of cellular oxidative processes, lactate may be inadequate or ineffective as a source of bicarbonate in patients suffering from acidosis associated with shock or other disorders involving reduced perfusion of body tissues.
When oxidative activity is intact, one to two hours time is required for conversion of lactate to bicarbonate.

The lactate anion is in equilibrium with pyruvate and has an alkalizing effect resulting from simultaneous removal by the liver of lactate and hydrogen ions.
In the liver, lactate is metabolized to glycogen which is ultimately converted to carbon dioxide and water by oxidative metabolism.

Sodium Lactate INS: 325
Function: Acidity Regulator, Antioxidant, Bulking Agent, Emulsifier, Humectant, Stabilizer, Thickener

Sodium lactate is the most cost effective, naturally occurring humectant available for use as a moisturizer.
Useful to adjust pH.
For bar soaps: hardens bar, reduces cracking, and increases moisture retention.
Recommended use level 0.5-5% for skin care products.
For bar soaps 2-3%. care products.

The sodium (Na+) ion combines with bicarbonate ion produced from carbon dioxide of the body and thus retains bicarbonate to combat metabolic acidosis (bicarbonate deficiency).
The normal plasma level of lactate ranges from 0.9 to 1.9 mEq/liter.

Sodium is the principal cation of extracellular fluid.
Sodium lactate comprises more than 90% of total cations at its normal plasma concentration of approximately 140 mEq/liter.
The sodium ion exerts a primary role in controlling total body water and Sodium lactates distribution.

Indications and Usage for Sodium Lactate
Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is primarily indicated, after dilution, as a source of bicarbonate for prevention or control of mild to moderate metabolic acidosis in patients with restricted oral intake whose oxidative processes are not seriously impaired.
Sodium lactate is not intended nor effective for correcting severe acidotic states which require immediate restoration of plasma bicarbonate levels.
Sodium Lactate has no advantage over sodium bicarbonate and may be detrimental in the management of lactic acidosis.

2-Hydroxypropanoic acid, monosodium salt
(2R)-2-Hydroxypropanoate (sodium)
E325
AI3-03131
Compound solution of Sodium Lactate
MFCD00065400
Sodium 2-Hydroxypropionate
CHEBI:75228
Propanoic acid, 2-hydroxy-, sodium salt (1:1)
(+/-)-2-Hydroxypropionic acid sodium salt
DL-Lactic acid sodium salt, 60% w/w syrup
sodium;2-hydroxypropanoate
Lactic acid, sodium salt
CHEMBL1357
NSC-31718

Sodium Lactate Injection, USP, 50 mEq (5 mEq/mL) is a sterile, nonpyrogenic, concentrated solution of sodium lactate (sodium lactate injection in aviva) in Water for Injection for additive use only after dilution by intravenous route as an electrolyte replen-isher and systemic alkalizer.
Sodium lactate should not be administered undiluted.
Sodium lactate (sodium lactate injection in aviva) is chemically designated as propanoic acid, 2-hydroxy-,monosodium salt and has the following structural formula:
CH3CH(OH)COONa
C3H5NaO3    112.1
A 60% aqueous solution is miscible in water.

Each mLcontains: Sodium lactate (sodium lactate injection in aviva) anhydrous 560 mg (5 mEq each of Na+ and lactate anion); Water for Injection q.s.
Hydrochloric acid and/ or sodium hydroxide for pH adjustment.

Sodium Lactate is found naturally in the stratum corneum of human skin.
When manufactured, Sodium lactate is most often produced through the fermentation of a source of sugar — for example, beets or corn.
The compound is subsequently derived by neutralizing the isolated lactic acid that results from the fermentation process.

Appearance: Clear light yellow liquid
Odor: None
Solubilities: Soluble in water
Boiling point: 105-110oC
Molecular weight: 112 g/mol
Weight per gallon: 10.9215 lbs/gal
Grades: Industrial, ACS, USP, FG, NF Grade

Sodium lactate is the sodium salt of lactic acid and is one of the hydrating substances that are produced by the skin to preserve the moisture and physiological pH.
Sodium lactate is used not only in cosmetics but also in the food industry as a humectant and an acid regulator.
On the skin, the growth of foreign microorganisms is inhibited by maintaining the skin’s natural acid barrier.
In addition, sodium lactate is a well-tolerated form of hydration that also keeps emulsions chemically stable.

Sodium lactate has a cushioning effect to stabilize the pH of foods.
Sodium lactate is also used in many foods as a seasoning to improve flavor.
Sodium lactate has excellent moisture-retaining effects that are not affected by temperature and humidity, which helps retain moisture even at low temperature and low humidity.
Sodium lactate is a colorless and clear syrupy liquid that is odorless or has a faint and unique odor.

Lactate is produced naturally by living organisms as a by-product of the glycolysis.
Jungbunzlauer sodium L(+)-lactate is an effective humectant and provides exceptional moisturisation due Sodium lactates high water holding capacity and buffering properties.
Sodium lactate is particularly suitable for skin care formulations and is ideal for natural formulations due to being ECOCERT/COSMOS approved.

Key benefits
• Intensely hydrates dry and dehydrated skin
• Multifunctional – functions as a preservative enhancer, buffering agent, and a humectant moisturiser.
• Prevents trans epidermal water loss
• Brighten the complexion with a healthy, hydrated glow
• Helps the skin to maintain a healthy pH level

Lactic acid, sodium salt (VAN)
EINECS 200-772-0
EINECS 206-231-5
NSC 31718
Sodium lactate [USP:JAN]
Mediject L
SodiumDL-lactate
Sodium lactate in plastic container
Mediject L (TN)
Purasal S/SP 60
Sodium lactate (7CI)
C3H5NaO3
EC 200-772-0
Sodium lactate 1/6 molar in plastic container
SCHEMBL4360

INCI: Sodium Lactate
Sodium lactate is the sodium salt of lactic acid, which is formed by lactic fermentation of sugars.
60% solution.

Sodium lactate is used as a natural additive in cold-process soap production.
Sodium lactate hardens the soap faster, facilitates Sodium lactates removal from the mold and improves Sodium lactates final texture.
Usage rate: add 1% into the caustic soda solution at 35ºC.
You can see how to use this ingredient in the video below.

Sodium Lactate E325 can be used in Food, Beverage, Pharmaceutical, Health & Personal care products, Agriculture/Animal Feed/Poultry.
Sodium lactate, E325, the sodium salt of lactic acid, used as food preservative, acidity regulator, and bulking agent to enhance flavor, inhibit the growth of pathogenic bacteria, and extend the shelf life of products.
Sodium lactate is often used in the production process of meat and grains.

Synonyms: DL-Lactic acid sodium salt , (±)-2-Hydroxypropanoic acid sodium salt , (±)-2-Hydroxypropionic acid sodium salt , (±)-Lactic acid sodium salt
Formula: H₃CCH(OH)COONa
MW: 112,06 g/mol
Density: 1,263 g/cm³ (20 °C)
Storage Temperature: Ambient
MDL Number: MFCD00065400
CAS Number: 72-17-3
EINECS: 200-772-0

Sodium Lactate has strong antimicrobial and humectant properties, making Sodium lactate an excellent emollient in skin care products.
Recommended usage is 1-5%.
Sodium Lactate is also used in soap making to produce a harder, longer lasting bar and help prevent cracking.
Sodium lactate will produce a creamier bar with a fast curing time, and also helps with de-molding.
Use up to 1 tsp per 454 grams (1 lb) of oils in soap.
Sodium Lactate 60 is a 60% solution in water.

Sodium lactate is the sodium salt of lactic acid, is a natural humectant and moisturiser and is a part of our own NMF (natural moisturising factor).
Sodium lactate is applied in cosmetic formulations for Sodium lactates moisturising functions and to adjust the pH (specially when buffering is needed).
In certain cosmetic products, the pH of the product might change with time and this would lead to destabilization of some certain ingredients.
This happens very often by applying urea or weak acid based emulsifiers and ingredients (citrate derivatives for example: glyceryl oleate citrate).
In such cases you need to stabilize the pH with a buffering system (blending sodium lactate and lactic acid)
Buffered solutions resist changes in pH upon addition of small amount of acids or bases.
Our blood for instance is a buffered system and Sodium lactates pH would not easily change.

Sodium lactate (JAN/USP)
Sodium lactate 0.167 molar in plastic container
INS NO.325
DTXSID6052829
INS-325
Pharmakon1600-01300036
Sodium DL-lactate, 60% solution
2-hydroxypropionic acid sodium salt
Lactic acid, monosodium salt (8CI)
NSC760108
AKOS015915154
HY-111095B
NSC-760108
AK121770
O584

Sodium lactate liquid is a salt that helps produce a harder bar of cold process soap and helps to release the finished soap from the mold.
Sodium lactate is also a great addition to lotions to replace the glycerin in the formula.
Add sodium lactate to your cooled lye/water before blending with oils.

Sodium Lactate is one of the skin’s Natural Moisturizing Factors (NMFs) and the sodium salt of lactic acid.
Sodium lactate is a great humectant because Sodium lactate binds water easily, but is also important in maintaining the skin’s acid mantle.
Sodium lactate keeps the skin’s pH below 5, which is the optimal ph level to limit microbial growth and even fight UV damage.
Sodium lactate is also keratolytic, meaning Sodium lactate helps remove dead skin cells from the surface of the skin, improving the appearance of the skin and contributing to Sodium lactates overall healthy function (without removing dead skin cells, your skin attempts to hydrate those dead cells -making hydration more difficult).
Sodium Lactate is usually used as a less tacky alternative for Glycerin.

Feature of Sodium lactate:
Sodium lactate is the sodium salt of lactic acid, which has a light salty taste and is a colorless transparent liquid.

Advantages
1. A natural moisturizing factor.
2. Sodium lactate is commonly used as a preservation, flavoring agent, moisturizer, etc. in food processing.
Sodium lactate is used for moisturizing, balancing pH, antifreeze and glycerin substitutes in industrial and medical applications.

Description: Sodium lactate is found in the stratum corneum of the skin and is the most cost effective, naturally occurring humectant available for use as a moisturizer.
Has slight skin-lightening effects.
Useful to adjust pH.
For bar soaps: hardens bar, reduces cracking, and increases moisture retention.
Recommended use level 0.5-5% for skin care products.
For bar soaps 2-3%. care products.

INCI Name: Sodium Lactate
CAS: 72-17-3, 867-56-1

DESCRIPTION of Sodium lactate:
Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste.

Description of Sodium lactate:
Sodium lactate is an amazing ingredient in all types of skincare.
In soaps, Sodium lactate creates a harder bar that lasts longer in the shower.
Sodium lactate also helps in making the unmolding of soaps easier from the soap mold.
Sodium lactate is truly a must-have ingredient for any soap maker!
Sodium lactate is a liquid salt derived from sugars such as beets and corn.

APPLICATION
S 2065 (OTTO) Sodium lactate 60% solution Cas 72-17-3 -used in shampoo products and other similar items such as liquid soaps as Sodium lactate is an effective humectant and moisturizer.

Specifications:
Appearance: Clear liquid, no turbidity.
Odor: Essentially odorless
Content: 58-62%
pH 7.5 -9.0
Boiling point: 112.38°C
Specific Gravity: 1.31
Solubility in water: Soluble

Synonyms
2-Hydroxypropanoic acid, monosodium salt; Propanoic acid, 2-hydroxy-, sodium salt (1:1); Lacolin; Lactic acid sodium salt
Lactic acid, monosodium salt; Lactic acid, sodium salt (VAN); Monosodium 2-hydroxypropanoate; Monosodium lactate; Per-glycerin
Propanoic acid, 2-hydroxy-, monosodium salt; Sodium alpha-hydroxypropionate; Sodium lactate 0.167 molar in plastic container
Sodium lactate 1/6 molar in plastic container; Sodium lactate in plastic container; [ChemIDplus] 2-Hydroxypropanoic acid sodium salt (1:1); [Merck Index]

Use: Sodium lactate has bacteriostatic properties; therefore, incorporating sodium lactate in cosmetic formulations can lead to more stability in bacterial growth.
Sodium lactate can be used as pH regulator for toiletry products like bath foam and soap.
Sodium lactates humectant action can reduce the moisture loss during the storage of the products and prevent the occurrence of cracked surface.
Recommended usage: 2% to 8%.
One of our customers uses Sodium lactate at 4% and is quite satisfied with her results.

About this substance
Helpful information
Sodium lactate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
Sodium lactate is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses of Sodium lactate
Sodium lactate is used in the following products: cosmetics and personal care products, inks and toners, leather treatment products, paper chemicals and dyes and pharmaceuticals.
Other release to the environment of Sodium lactate is likely to occur from: indoor use as processing aid.

Widespread uses by professional workers of Sodium lactate
Sodium lactate is used in the following products: plant protection products, polishes and waxes, washing & cleaning products, inks and toners, leather treatment products, paper chemicals and dyes and cosmetics and personal care products.
Sodium lactate is used in the following areas: agriculture, forestry and fishing.
Other release to the environment of Sodium lactate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.

Formulation or re-packing of Sodium lactate
Sodium lactate is used in the following products: cosmetics and personal care products, metal surface treatment products, non-metal-surface treatment products, plant protection products, semiconductors and washing & cleaning products.
Release to the environment of Sodium lactate can occur from industrial use: formulation of mixtures.

Uses of Sodium lactate at industrial sites
Sodium lactate is used in the following products: metal surface treatment products, non-metal-surface treatment products and semiconductors.
Sodium lactate is used for the manufacture of: chemicals and electrical, electronic and optical equipment.
Release to the environment of Sodium lactate can occur from industrial use: in processing aids at industrial sites and as processing aid.

Lactic acid sodium salt produced naturally through the fermentation of sugars.
Clear and viscous liquid, slight odor.
Emulsions: used as a co-preservative.
Soaps: used for hardening soaps faster, making them last longer and giving them a more glossy finish.
Soluble in water and alcohol.
Sodium lactate is a combination of 60% sodium lactate and 40% water.

INCI: Sodium lactate
Properties: Antioxidant, bacteriostatic agent (stabilizes bacterial levels), pH control agent, humectant.

The effects of sodium lactate in soaps
-On pigments and other dyes: lactate can pale the shades of pigments and micas used for coloring soaps.
These effects are very light and generally imperceptible.
-In the molds: The temperature rises in the molds, but no signs of fragrance degradation or other consequences have been observed.
Lactate helps demolding soaps made in individual molds.
-On hardness and cutting: soap hardens much faster with sodium lactate than without Sodium lactate.
Sodium lactate is therefore recommended to demold and cut the soaps as soon as possible.
Generally, the soaps are ready to be cut after 18 hours, unlike 24 hours or more without lactate.
-On the weight of soaps: soaps made with sodium lactate will lose less water and shrink less than a soap made without lactate.
-Feel and other effects: sodium lactate gives soap a silky effect and a soft feel in addition to giving Sodium lactate moisturizing properties.
Note that no effect on the quantity or quality of the foam has been observed.
Sodium lactate does not affect the pH of the soap.
-Trace: caution, sodium lactate quickly makes a thick paste.
Sodium lactate is recommended for opaque soaps that do not need to be worked.
Sodium lactate is not recommended for marbling techniques that require a more liquid paste.

Use: Must be added to the aqueous phase and be heated to ensure proper incorporation.
Concentration: 1-3%.

Manufacture
Release to the environment of Sodium lactate can occur from industrial use: manufacturing of the substance.

A multiple electrolyte, isotonic, crystalloid solution for intravenous infusion containing sodium chloride, potassium chloride, calcium chloride dihydrate, and sodium lactate, which can restore the electrolyte balance, normalize pH, and provide water for hydration.
Upon intravenous administration, the compound sodium lactate solution will replace any lost body fluids and electrolytes thereby providing hydration as well as normalizing electrolyte concentrations.
In addition, conversion of sodium lactate to bicarbonate increases plasma bicarbonate levels, which facilitates the removal of hydrogen ions from the blood stream, raises blood pH and normalizes the acid-base balance.

Synonyms: 2 -Hydroxypropanoic Acid, Monosodium Salt, 2 -Hydroxypropanoic Acid, Sodium Salt, E 325, Lactic Acid, Sodium Salt, Propanoic Acid, 2 -Hydroxy -, Monosodium Salt, Sodium 2 – Hydroxypropanoate, Sodium L (+) Lactic Acid, Sodium Lactate, Sodium Salt of Lactic Acid
INCI: Sodium Lactate
Chemical formula: NaC3H5O3
CAS #: 72-17-3

Other appellations
Sodium lactate | Sodium lactate (hydratant)

Sodium Lactate is the sodium salt of natural L (+) lactic acid made by the fermentation of sugar.
Sodium lactate has antimicrobial properties and is pH neutral.
This product is widely used as a natural preservative in many applications.
Best if used within 24 months of the manufacture date.

SODIUM LACTATE is classified as :
Buffering
Humectant
Keratolytic

CAS Number: 72-17-3 / 867-56-1
EINECS/ELINCS No: 200-772-0 / 212-762-3
COSING REF No: 79577
INN Name: sodium lactate
Chem/IUPAC Name: Sodium lactate

Sodium lactate, when added to your Cold Process soap recipe helps to give a stable bar of soap with great lathering, a wonderful feel, and makes Sodium lactate easy to remove from your silicone mould.
When used in lotions and cream also gives them a great silky feel when they are used, and Sodium lactates humectant qualities help to bind the moisture to your skin for better hydration.
Sodium lactate is a multifunctional ingredient that is commonly used in cosmetics and skincare products.
Sodium lactate helps to improve the stability of a formulation but also has the added benefit of pulling water-based moisture into the skin.
The main functions of sodium lactate are as a preservative enhancer, buffering agent, and humectant moisturizer.

Sodium lactate is the sodium salt of lactic acid.
With a hydroxyl group adjacent to the carboxyl group, lactic acid is classified as an alpha-hydroxy acid (AHA).
Sodium lactate is also a natural component of the top layers of the skin and functions as part of the NMF or Natural Moisturizing Factor.
In addition to sodium lactate, the NMF consists of amino acids, sugars, and electrolytes that work to keep skin’s surface intact, supple, and hydrated.
The NMF becomes depleted as we age, as well as from routine exposure to sensitizing ingredients like drying cleansing agents and denatured alcohol.
This leads to visibly dry, tight-feeling, flaky skin.
Thus, replenishing the skin with natural components of the NMF, such as sodium lactate, can help to correct these problems.

Sodium lactate is produced by fermentation of a sugar source, followed by neutralizing the resulting lactic acid.
While the names may sound similar, sodium lactate is not chemically similar to lactose or the sugar present in milk.
In fact, most commercially used lactic acids are fermented from dairy-free products such as cornstarch, potatoes, or molasses.
In addition to use in cosmetics, sodium lactate functions as a preservative, acidity regulator, and bulking agent when added to food.
Furthermore, sodium lactate is used in the medical field to treat arrhythmias and metabolic acidosis.

THE GOOD:Sodium lactate helps to pull water based moisture into the skin, giving Sodium lactate a hydrated, healthy appearance.
Sodium lactate also helps to stabilize formulations by buffering pH and acting as a preservative.
THE NOT SO GOOD:Sodium lactate can mildly increase your sensitivity to the sun so make sure you apply enough sunscreen.
WHO IS Sodium lactate FOR?All skin types except those that have an identified allergy to Sodium lactate.
SYNERGETIC INGREDIENTS:Works well with most ingredients.
KEEP AN EYE ON:Nothing to keep an eye on here.

Inci name
Sodium lactate
French name
Sodium Lactate

Sodium Lactate likely one of the most useful ingredients you never knew you needed!
A liquid salt, Sodium Lactate is added to lye water to hasten the drying and hardening process and create a strong, luxurious lather.
The addition of this product results in harder, longer-lasting bars of soap that dries quicker and unmoulds with ease, ensuring a perfect, unblemished result that cuts cleanly every single time.
Heirloom’s Sodium Lactate is perfect for soft oil soap, palm-free soap and Castile soap, preserving structural integrity, ensuring a clean appearance and reducing cure time.
Use at a rate of 2-5% for the perfect amount.

Sodium Lactate is also a wonderful addition to lotions and creams.
Want a thicker, velvety-soft product that provides deeper, long lasting hydration?
Add Sodium Lactate! Our Sodium Lactate additionally reduces the stickiness of glycerine-heavy recipes.
A little goes a long way: use at 1-3% of the total recipe.
This product is derived from corn syrup using non genetically modified product.
This is the standard 60% product required by most recipies.
CAS Number: 72-17-3
This product is food grade (when bought in original packaging), vegetarian, vegan, Kosher compliant and certified and Halal compliant and certified.

A novel absorbent sodium lactate (NaLa) aqueous solution (aq) for SO2 absorption is reported.
SO2 in simulated flue gas is reversibly absorbed in NaLa aq.
The absorption capacity of SO2 in the absorbent increases with increasing NaLa content and SO2 concentration, and decreasing temperature.
Compared with the absorbents reported in the literature, the absorption capacity of SO2 in NaLa aq. is much high, for example, 50 wt % NaLa aqueous solution can absorb 0.130 g SO2/g absorbent at a SO2 concentration of 2.5 vol % and 40 °C.
Importantly, NaLa (aq) exhibits high reversibility and long-term stability, indicating a promise for the desulfurization of flue gas.
The absorption mechanism is proposed to be the replacement of lactic acid (HLa) by sulfurous acid (H2SO3), which is generated by dissolving SO2 in water.

The soluble salt of Lactic acid (milk acid) was discovered over 200 years ago in fermented milk (Sodium lactate is known that Cleopatra and others used to bath in sour milk to obtain beautiful skin).
Lactic acid is an alpha-hydroxy acid commonly found in milk and other foods made by fermentation of a sugar source.
A colourless natural substance, Sodium lactate helps with exfoliation, leaving skin with a rejuvenated appearance.
Sodium lactate can help reduce the effects of photo-aging, and can play an important role in the treatment of sun-damaged skin.
Sodium lactate is commonly used to extend shelf life as Sodium lactate has a broad antimicrobial action and is effective at inhibiting most spoilage and pathogenic bacteria and works as a humectant and pH control agent.
Sodium lactate does not need to be avoided by those with milk allergy.

Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH).
This mixed isomer lactate has been qualified for use in mouse embryo culture.
Lactate regulates pyruvate uptake and metabolism in the preimplantation mouse embryo.

Sodium Lactate is the sodium salt of natural L (+) lactic acid made by the fermentation of sugar.
Sodium lactate has antimicrobial properties and is pH neutral.
Sodium lactate is widely used as a natural preservative in many applications.
Best if used within 24 months of the manufacture date.

Compound solution of Sodium Lactate [INN]
31-EP2272817A1
31-EP2287160A1
31-EP2301938A1
31-EP2311821A1
31-EP2372017A1
31-EP2374895A1
DB-079226
DL-Lactic acid sodium salt, 60% in water
CS-0102489
E 325
E-325
FT-0656540
FT-0689056
FT-0771022
S0928
Sodium DL-lactate, 60% w/w aqueous solution
D02183
Q418235
2-Hydroxypropionic acid sodium salt, 60% in water
Propanoic acid, 2-hydroxy-, monosodium salt (9CI)
W-104498

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